PRESS RELEASE: MOLOGEN AG: Final results from renal cancer trial with MGN1601 presented at ASCO Genitourinary Cancers Symposium
DGAP-News: MOLOGEN AG / Key word(s): Study MOLOGEN AG: Final results from renal cancer trial with MGN1601 presented at ASCO Genitourinary Cancers Symposium
03.02.2014 / 09:07
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MOLOGEN AG: Final results from renal cancer trial with MGN1601 presented at ASCO Genitourinary Cancers Symposium
- Treatment with MGN1601 safe and well tolerated
- Promising median overall survival data in a subgroup of patients
- Presentation at ASCO - GU attracted great interest
Berlin, February 3, 2014 - Final results from the phase I/II clinical study with MGN1601 (ASET trial) have been presented in a poster at the 2014 Genitourinary Cancers Symposium. The trial evaluated safety and tolerability of MGN1601 in 19 heavily pretreated patients with advanced renal cancer which had no other treatment options. The monotherapy with tumor cell-based cancer vaccine MGN1601 was well tolerated and safe. Furthermore, treatment with MGN1601 resulted in promising median overall survival data in a subgroup of patients. One patient achieved a long term partial response and another patient up to 60 weeks with disease control. Putative predictive biomarkers were identified from pre-treatment characteristics, which were associated with longer overall survival. Those may allow identifying patients more likely to benefit from this innovative vaccination approach with MGN1601.
In total 19 patients were included into the study and received at least one MGN1601 injection (ITT population). 10 patients completed the study per protocol (PP population). 9 patients discontinued the study early without completing the planned treatment phase due to the worsening of their tumor disease (non-PP population).
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PRESS RELEASE: MOLOGEN AG: Final results from -2-
03.02.14 07:00 Dow Jones Newswires
PRESS RELEASE: AURELIUS successfully closes sale of brightONE's Healthcare operations to T-Systems
DGAP-News: AURELIUS AG / Key word(s): Acquisition AURELIUS successfully closes sale of brightONE's Healthcare operations to T-Systems
03.02.2014 / 07:00
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AURELIUS successfully closes sale of brightONE's Healthcare operations to T-Systems
- Successful closing of the transaction on January 31, 2014
- Additional transactions planned in coming months
Munich, February 3, 2014 - The Munich-based AURELIUS Group (ISIN DE000A0JK2A8) successfully closed the sale of the Healthcare operations of its subsidiary brightONE to T-Systems International GmbH ('T-Systems'). After the transaction was agreed between AURELIUS and T-Systems on December 20, 2013, it has now also been approved by the responsible antitrust authorities. For T-Systems, Deutsche Telekom AG's IT subsidiary, this acquisition is another important step on the way to becoming an integrated provider of IT healthcare. T-Systems received access to these strategically markets as a result of its takeover of brightONE Healthcare's German and Dutch units. In addition, T-Systems is also taking over brightONE Healthcare's Service and Maintenance business, which is run from India.
AURELIUS took over brightONE in July 2013 from the Finnish-based Tieto Group and has since supported the group in its reorientation as a provider of innovative IT and engineering solutions. brightONE had last taken over Telenet GmbH Kommunikationsysteme, thereby further expanding its activities in the areas of Customer Experience Management and Testing Solutions.
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PRESS RELEASE: AURELIUS successfully closes sale of brightONE's Healthcare operations to T-Systems
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