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Volcano Highlights Two Products Intended to Expand the Role of Physiology in the Cath Lab

SAN DIEGO -- Volcano Corporation (NASDAQ: VOLC) a leading developer and manufacturer of precision guided therapy tools designed to enhance the diagnosis and treatment of coronary and peripheral vascular disease, today announced that it will demonstrate the Verrata Pressure Guide Wire and the iFR (Instant wave-Free Ratio) modality throughout the week during the EuroPCR 2013 Congress in Paris, France. These two interventional tools are intended to help physicians guide more procedures and make more decisions based on actual heart function, rather than relying on the angiogram alone.

"Despite all the questions that surround percutaneous coronary interventions (PCI) today, there is an exciting evolution taking place in the form of more precise stenting decisions and guidance with physiology tools like Fractional Flow Reserve (FFR)," commented Joe Burnett, Executive Vice President and General Manager of the Functional Management Business Unit at Volcano. "Data from the DEFER, FAME and FAME II trials have repeatedly provided evidence that FFR is the best and most evidence-based diagnostic tool available to help properly diagnose a patient's vessel, or even a specific blockage. In the five years since FAME, it is increasingly uncommon that a physician makes a decision based on angiography alone, without some sort of functional assessment being performed. We believe that FFR is the most proven vessel-specific assessment available."

"Physiology will continue to evolve," added Burnett. "Even though FFR is routinely used to decide if a patient needs treatment, daily practice often reverts back to the basic angiogram to select which lesions get treated and to confirm the treatment was successful. There is a tremendous amount of information physiology can provide that we have yet to unlock in daily practice. The Verrata wire and iFR modality are designed to continue that evolution to allow physicians to quickly and easily get valuable functional information throughout a stent procedure."

The Verrata ressure Guide Wire will be Volcano's fifth new pressure guide wire in the past five years. It embodies a new wire design and workflow designed to facilitate fast, simple connections and re-connections throughout a procedure. "The proposed workflow of the new wire is ideal because it would more closely mimic standard guidewire use in everyday practice," commented Bruce Samuels, MD of Cedars-Sinai Hospital in Los Angeles, CA. "The biggest difference between an everyday interventional wire and a pressure wire is the large, heavy connector that resides on the end. The design of the new Verrata wire would allow me to very quickly and easily disconnect and reconnect the wire with no interruption to my workflow. Re-connecting a pressure wire is now faster than re-connecting the indeflator for a stent delivery system, which would allow me to steer the Verrata wire just like a standard interventional wire with no connector, and simply reconnect any time I want to take a measurement. This is ideal for delivering devices like balloons and stents over the wire, and then making valuable physiologic measurements after each step. I can forsee the functional improvement that my therapy will have on the patient and not be forced to only trust the angiogram."

Our new iFR software modality was developed in concert with Imperial College London. Using the same pressure wire and equipment currently used for FFR, iFR amplifies the patient's physiologic measurements during resting conditions before stressing the heart with a commonly used vasodilator drug, like Adenosine.

"I continue to be amazed at how inaccurate the angiogram can be," commented Matthias Gotberg, Interventional Cardiologist, Department of Coronary Heart Disease, Skane University Hospital, Lund, Sweden. "Physiology uncovers very important functional information that simply disagrees with the angiogram and should not be ignored. By making this meaningful measurement in seconds, physicians can get physiologic answers, but in a workflow almost identical to how they perform angiographic PCI today. In essence, you can repeatedly double-check the angiogram with actual heart function and add very little time to your procedure. I have had access to the live software for more than three months now. Quite simply, today I am making functional measurements with iFR that before I would have left to angiography alone."

"iFR and FFR look at the same lesion, but from two different viewpoints," said Justin Davies, MBBS, MRCP, PhD, of Imperial College London. "FFR will always be an important tool for us in the lab. It creates a 'worst-case-scenario' to rule out ischemia, and patients with a negative FFR test do very well clinically with medical therapy alone. At the same time, retrospective iFR core lab analysis in over 1,500 patients suggests that more than half of our patients could avoid the need for hyperemic drugs and still benefit from the proven value of these physiologic assessments. ADVISE II will be the very first prospective, multi-center independent study using the currently available Volcano/Imperial iFR algorithm to seek to confirm this hypothesis."

Results from the first 300 ADVISE II patients will be presented at EuroPCR as part of the Hot Line late-breaking clinical trial session on Thursday, May 23rd at 10:09 AM in Room 351.

Both the Verrata Pressure Wire and the iFR software modality will be compatible with Volcano's multi-modality imaging systems including the latest CORE Integrated System which will also be on display at EuroPCR 2013. iFR is currently active in more than 20 centers around the world. Hospitals in London, Rotterdam and Johannesburg will be transmitting live iFR cases throughout this week at PCR. "These two new tools will make physiology more accessible and mainstream, and that is a good thing for hospitals and patients," continued Burnett. "The easier it is for a physician to double-check the angiogram, the better. Having both iFR and FFR on the same system, just one click away, only expands the options to do so. This is a very exciting time for Volcano's physiology program as we are executing our vision of a frontline interventional wire workflow that can quickly and easily provide functional information beyond angiography."

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Verrata(TM) Pressure Guide Wire and iFR® Instant Wave-Free Ratio(TM) Software ...

RESTON, Va.--(BUSINESS WIRE)--

ServInt, a pioneering provider of managed cloud hosting for businesses worldwide, today announced it is providing all its customers with a free subscription to StopTheHacker malware detection software a service with an annual cash value of $120. Customers are being granted one free subscription for each server they lease through ServInt, and each subscription allows customers to monitor malware activity on one domain.

The free StopTheHacker package being offered allows ServInt customers to determine whether the pages under monitored domains are being affected by known malware and viruses, and will also check to see if those domains are being blacklisted by major search engines.

In our opinion, malware is the number one external threat faced by todays online businesses, said ServInt Director of Network Compliance Mike Witty. In addition to the damaged reputations businesses suffer when their site unwittingly does harm to their customers, blacklisting by major search engines results in those sites losing all the SEO and general goodwill they may have earned over the years. We think offering our clients access to protection from these threats is a basic business obligation.

StopTheHackers technology, supported by the U.S. National Science Foundation, has won multiple awards since 2009. StopTheHacker serves customers worldwide, protecting their online presence from emerging threats.

The exact feature set of the latest StopTheHacker product version and editions can be found at stopthehacker.com/packages.

About StopTheHacker

Based in San Francisco, StopTheHacker is one of the tech industrys most watched startups, a provider of SaaS services focused on cyber warfare in the arenas of web malware, security and reputation protection. StopTheHackers Artificial Intelligence and Machine Learning based technology is supported by the National Science Foundation and has won multiple awards since 2009. Gaining rapid momentum, StopTheHacker has become widely recognized and respected as an industry leader, protecting website owners ranging from large multi-nationals to web hosting companies and small business owners, all of which are vulnerable to global hacker attacks.

About ServInt

ServInt is a pioneering provider of high-reliability, managed cloud hosting services for enterprises worldwide. Founded in Northern Virginia in 1995, ServInt provides a range of IaaS, PaaS, VPS and dedicated server packages to hosting service resellers, web designers, developers and online businesses in more than 130 countries. To learn more about ServInts cloud, VPS and dedicated hosting solutions, please call 1-800-573-7846 from the USA, +1-703-847-1381 from outside the USA or visit http://www.servint.net.

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ServInt to Provide Free StopTheHacker Malware Detection to All Its Customers

Freely available software tools can be bundled with malware designed to steal data, including account credentials, according to a Microsoft researcher who discovered and analyzed a password stealer bundled with an online gaming tool.

A password stealing Trojan called USteal was detected in a gaming tool used to customize Dota2, a Valve Corporation online battle game. A third-party distributed the software to users who wanted customize the gaming experience, wrote Alden Pornasdoro, of Microsoft's Malware Protection Center team.

"It is important to be aware of this risk, and understand just how easy it can be for malware authors to create malicious software bundles," Pornasdoro wrote in his analysis of USteal.

"Once a Trojan is created with the builder, an author can choose to bundle the malware with legitimate tools, software or images," Pornasdoro wrote, adding that distribution is up to the malware's creator. "It could be as simple as uploading the file to a free hosting site and freely spam the link on forums, as comments or as instant messages. The distribution method depends on an attacker's target."

Russia ranked the highest for USteal malware infections with more than 60,000 of them, followed by the United States with more than 11,000 infections. Microsoft recommends users download software directly from the software maker's official website. Avoid links from forum posts because they can lead to repackaged, malware-laden software, Pornasdoro said.

Version 13 of the Microsoft Security Threat Report highlighted the technique of bundling malicious software in legitimate software applications. The technique has been popular with adware designed to send system data and an individual's browsing habits to an aggressive ad network without the victim's consent.

OpenCandy, an adware program, was detected running with some third-party software last August. DealPly, another program that displays search results based on a user's browsing habits, was labeled adware by Microsoft. It was being bundled with third-party applications as a browser add-on.

Mobile devices are also not immune, with freely available versions of legitimate mobile applications sometimes packaged alongside mobile spyware. Microsoft warned Android users earlier this year that a rootkit was detected bundled in a legitimate Android application. Gingermaster, a threat detected with certain clean applications, apparently contained a malicious image file that could root the device. A Google update now blocks the attack. The notorious DroidDream infection was also detected embedded in otherwise harmless applications.

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Microsoft Warning: Free Software Could Contain Hidden Malware

LOS GATOS, CA--(Marketwired - May 29, 2013) - Codice Software, creators of the enterprise oriented Distributed Version Control System (DVCS) called Plastic SCM, today launched Semantic Merge for Java. First available to developers using C# and Visual Basic .NET, Semantic Merge is now available to developers using Java, one of the world's most popular programming language with a market share of 27.5 percent, according to the May 2013 PYPL Popularity of Programming Index. Java also ranked a close second in the May 2013 TIOBE Community Programming Index, another indicator of its popularity. Semantic Merge will be available to open source contributors for free.

Every day, millions of lines of code are written, modified, moved and reorganized as developers update and create new features in games, devices and applications. In order to improve code quality and readability throughout the software lifecycle, developers engage in refactoring, a software practice that requires frequent structure changes. Modern agile software development is based on coders' ability to work in parallel on the same codebase and perform concurrent changes, potentially inside the same files that need to be merged back together.

With Semantic Merge, software coders can reach new levels of productivity by easily tracking and preserving all changes performed concurrently, ensuring that all code is assembled back together precisely. Using advanced merge technology built into Codice Software's signature product, Plastic SCM, Semantic Merge makes it easy to consolidate files that are heavily refactored in parallel by different developers, regardless of the code programming language. The merge tool can also be configured for use with Git, Subversion, Perforce, ClearCase, Team Foundation Server, Mercurial and many others.

All other merge systems today use text-based algorithms that don't identify the programming language the code is written in but just the modifications to text. The inability for merge tools to fully understand programming language structures means they are heavily dependent on the position of the texts being modified, which greatly restricts developers' ability to perform concurrent changes and improve code quality and readability by refactoring.

"Since the launch of Semantic Merge for C# and Visual Basic.NET last month, we've received extremely positive feedback from developers," said Francisco Monteverde, CEO of Codice Software. "They have been waiting for a tool like this for a long time because it greatly improves productivity. By simplifying code merges, developers spend up to 97 percent less time reviewing code. We have more than doubled the reach of Semantic Merge now that Java developers can use it, and anticipate strong interest and usage of it with its free, full license for contributors to open source projects."

About Codice Software

Codice Software is a privately held software development company that provides the freedom, flexibility and security for distributed teams to enable agile development in parallel. Its enterprise-class Plastic SCM platform increases collaboration between developers and boosts productivity, time to market and quality of code. It lets developers work more quickly and collaborate seamlessly across platforms, languages and locations. Its customers include software development teams across mobile, gaming, financial services, energy and utilities and enterprise software such as Pantech, Digital Legends, Ricardo and HP. Codice Software's international marketing and sales headquarters are located in Silicon Valley. For more information, please visit http://www.codicesoftware.com.

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Codice Software Launches Semantic Merge for Java and Announces Full, Free License for Open Source Contributors

BUCHAREST, ROMANIA--(Marketwired - May 29, 2013) - Bitdefender, the creator of innovative global antivirus software solutions, today announced that it will offer LinkedIn members access to free security software via the LinkedIn Safety Center. The LinkedIn Safety Center is designed to provide LinkedIn's more than 225 million members with the tools and knowledge to protect their identity and data on the Internet.

"Businesses and professionals are the high-value targets that online criminals seek out for bank fraud, identity theft, account hijacking and other cyber crime," said Bitdefender Chief Security Strategist Catalin Cosoi. "We've been developing innovative technologies and strategies to fight these crimes for more than a decade, and we're eager to help."

Through the LinkedIn Safety Center, Bitdefender is offering small businesses and individuals complete security from malware, phishing and other malicious online activity for three months through free trials of two flagship products.

Bitdefender Cloud Security for Small Businesses deploys Bitdefender's award-winning anti-malware technology to protect small business networks with remote control PC protection, anti-phishing technology, productivity controls and other features tailored to business users.

Bitdefender Total Security 2013 offers LinkedIn members protection on social networks, access to the world's most effective anti-malware technology, a fine-tuned spam filter, antiphishing, chat encryption and more.

Bitdefender leads the industry with its acclaimed technologies. In April, testing by independent antivirus analysis firm AV Comparatives, Bitdefender was the only one of the 21 participants to catch 100% of the malware thrown at it. The result came a month after Bitdefender scored the #1 spot in trials by AV-TEST, the other major independent analysis firm, with a perfect score.

In an awards ceremony earlier this year, Bitdefender was named Product of the Year for 2012 by AV-Comparatives, after it scored a perfect three stars in eight rounds of testing.

About Bitdefender

Bitdefender is the creator of one of the world's fastest and most effective lines of internationally certified internet security software. The company is an industry pioneer, introducing and developing award-winning protection since 2001. Today, Bitdefender technology secures the digital experience of around 400 million home and corporate users across the globe.

Recently, Bitdefender won a series of important awards and accolades in the global security industry, including "Product of the Year" by AV-Comparatives, "Best Repair 2012" by AV-TEST, and "Editor's Choice" by PC Mag, that confirmed the antivirus software's leadership status among security products. More information about Bitdefender's products is available from the company's security press room. Additionally, Bitdefender publishes the HOTforSecurity blog, where readers can find stories from the underworld of internet fraud, scams, malicious software -- and gossip.

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Bitdefender to Provide Free Security Software on LinkedIn Safety Center