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Washington (CNN) -- Democrats have a message for voters during the final, frenzied day of campaigning: All is not lost.

Party leaders insist they can still hold onto the Senate -- their last bastion of power on Capitol Hill -- and are spending the remaining hours before the polls open on Tuesday trying to convince their voters not to give up.

"I don't agree with the oddsmakers," Vice President Joe Biden said in an exclusive interview with CNN Chief Political Analyst Gloria Borger. "I predict we're gonna ... keep the Senate."

Everything would have to break for Democrats just right for Biden's optimism to carry the day. New polls in states that Democrats must win if they have any hope of keeping the Senate aren't promising.

In New Hampshire, a WMUR poll released Sunday shows Democratic Sen. Jeanne Shaheen and Republican challenger Scott Brown in a deeply competitive race. The poll puts Shaheen's support at 46% with Brown at 43%. The race narrows further -- with Shaheen at 47% against Brown at 45% -- once undecided voters are asked who they are most likely to support.

The numbers are troubling for Democrats because a WMUR poll just a few days earlier showed Shaheen leading Brown 50% to 42%.

A Quinnipiac University poll in Iowa shows the Senate race there in a dead heat, with Democrat Bruce Braley and Republican Joni Ernst at 47%. That could provide some comfort to Democrats after a Des Moines Register poll had Ernst up by 7 points over the weekend.

Though Republicans appear on track to take the Senate majority for the first time in nearly a decade, polls can be wrong and might miss important shifts in the electorate during the final hours of the election.

But veteran Republican power broker Haley Barbour told CNN's "The Lead with Jake Tapper," that it was looking good for his side.

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Democrats may lose U.S. Senate