Archive for the ‘Machine Learning’ Category

New Machine Learning Theory Raises Questions About the Very Nature of Science – SciTechDaily

A novel computer algorithm, or set of rules, that accurately predicts the orbits of planets in the solar system could be adapted to better predict and control the behavior of the plasma that fuels fusion facilities designed to harvest on Earth the fusion energy that powers the sun and stars.

The algorithm, devised by a scientist at the U.S. Department of Energys (DOE) Princeton Plasma Physics Laboratory (PPPL), applies machine learning, the form of artificial intelligence (AI) that learns from experience, to develop the predictions. Usually in physics, you make observations, create a theory based on those observations, and then use that theory to predict new observations, said PPPL physicist Hong Qin, author of a paper detailing the concept in Scientific Reports. What Im doing is replacing this process with a type of black box that can produce accurate predictions without using a traditional theory or law.

Qin (pronounced Chin) created a computer program into which he fed data from past observations of the orbits of Mercury, Venus, Earth, Mars, Jupiter, and the dwarf planet Ceres. This program, along with an additional program known as a serving algorithm, then made accurate predictions of the orbits of other planets in the solar system without using Newtons laws of motion and gravitation. Essentially, I bypassed all the fundamental ingredients of physics. I go directly from data to data, Qin said. There is no law of physics in the middle.

PPPL physicist Hong Qin in front of images of planetary orbits and computer code. Credit: Elle Starkman / PPPL Office of Communications

The program does not happen upon accurate predictions by accident. Hong taught the program the underlying principle used by nature to determine the dynamics of any physical system, said Joshua Burby, a physicist at the DOEs Los Alamos National Laboratory who earned his Ph.D. at Princeton under Qins mentorship. The payoff is that the network learns the laws of planetary motion after witnessing very few training examples. In other words, his code really learns the laws of physics.

Machine learning is what makes computer programs like Google Translate possible. Google Translate sifts through a vast amount of information to determine how frequently one word in one language has been translated into a word in the other language. In this way, the program can make an accurate translation without actually learning either language.

The process also appears in philosophical thought experiments like John Searles Chinese Room. In that scenario, a person who did not know Chinese could nevertheless translate a Chinese sentence into English or any other language by using a set of instructions, or rules, that would substitute for understanding. The thought experiment raises questions about what, at root, it means to understand anything at all, and whether understanding implies that something else is happening in the mind besides following rules.

Qin was inspired in part by Oxford philosopher Nick Bostroms philosophical thought experiment that the universe is a computer simulation. If that were true, then fundamental physical laws should reveal that the universe consists of individual chunks of space-time, like pixels in a video game. If we live in a simulation, our world has to be discrete, Qin said. The black box technique Qin devised does not require that physicists believe the simulation conjecture literally, though it builds on this idea to create a program that makes accurate physical predictions.

The resulting pixelated view of the world, akin to what is portrayed in the movie The Matrix, is known as a discrete field theory, which views the universe as composed of individual bits and differs from the theories that people normally create. While scientists typically devise overarching concepts of how the physical world behaves, computers just assemble a collection of data points.

Qin and Eric Palmerduca, a graduate student in the Princeton University Program in Plasma Physics, are now developing ways to use discrete field theories to predict the behavior of particles of plasma in fusion experiments conducted by scientists around the world. The most widely used fusion facilities are doughnut-shaped tokamaks that confine the plasma in powerful magnetic fields.

Fusion, the power that drives the sun and stars, combines light elements in the form of plasma the hot, charged state of matter composed of free electrons and atomic nuclei that represents 99% of the visible universe to generate massive amounts of energy. Scientists are seeking to replicate fusion on Earth for a virtually inexhaustible supply of power to generate electricity.

In a magnetic fusion device, the dynamics of plasmas are complexand multi-scale, and the effective governing laws or computational models for a particular physical process that we are interested in are not always clear, Qin said. In these scenarios, we can apply the machine learning technique that I developed to create a discrete field theory and then apply this discrete field theory to understand and predict new experimental observations.

This process opens up questions about the nature of science itself. Dont scientists want to develop physics theories that explain the world, instead of simply amassing data? Arent theories fundamental to physics and necessary to explain and understand phenomena?

I would argue that the ultimate goal of any scientist is prediction, Qin said. You might not necessarily need a law. For example, if I can perfectly predict a planetary orbit, I dont need to know Newtons laws of gravitation and motion. You could argue that by doing so you would understand less than if you knew Newtons laws. In a sense, that is correct. But from a practical point of view, making accurate predictions is not doing anything less.

Machine learning could also open up possibilities for more research. It significantly broadens the scope of problems that you can tackle because all you need to get going is data, Palmerduca said.

The technique could also lead to the development of a traditional physical theory. While in some sense this method precludes the need of such a theory, it can also be viewed as a path toward one, Palmerduca said. When youre trying to deduce a theory, youd like to have as much data at your disposal as possible. If youre given some data, you can use machine learning to fill in gaps in that data or otherwise expand the data set.

Reference: Machine learning and serving of discrete field theories by Hong Qin, 9 November 2020, Scientific Reports.DOI: 10.1038/s41598-020-76301-0

Here is the original post:
New Machine Learning Theory Raises Questions About the Very Nature of Science - SciTechDaily

Using machine learning to find COVID-19 treatment options – Health Europa

The team have developed a machine learning-based approach to identify drugs already on the market that could potentially be repurposed to fight the virus. The system accounts for changes in gene expression in lung cells caused by both the disease and ageing.

The researchers have pinpointed the protein RIPK1 as a promising target for COVID-19 drugs and have identified three approved drugs that act on the expression of RIPK1.

The research has been published in the journal Nature Communications and the co-authors include MIT PhD students Anastasiya Belyaeva, Adityanarayanan Radhakrishnan, Chandler Squires, and Karren Dai Yang, as well as PhD student Louis Cammarata of Harvard University and long-term collaborator G.V. Shivashankar of ETH Zurich in Switzerland.

The researchers focused in on the most promising drug repurposing candidates by generating a list of possible drugs using a machine learning technique called an autoencoder then mapping the network of genes and proteins involved in both ageing and SARS-CoV-2 infection. They then used statistical algorithms to understand causality in that network, allowing them to pinpoint upstream genes that caused cascading effects throughout the network. Drugs targeting those upstream genes and proteins should be promising candidates for clinical trials.

Making new drugs takes forever, says Caroline Uhler, a computational biologist in MITs Department of Electrical Engineering and Computer Science and the Institute for Data, Systems and Society, and an associate member of the Broad Institute of MIT and Harvard. Really, the only expedient option is to repurpose existing drugs.

Uhler and Shivashankar suggest that one of the main changes in the lung that happens through ageing is that it becomes stiffer. The stiffening lung tissue shows different patterns of gene expression than in younger people, even in response to the same signal.

Uhler said: Earlier work by the Shivashankar lab showed that if you stimulate cells on a stiffer substrate with a cytokine, similar to what the virus does, they actually turn on different genes. So, that motivated this hypothesis. We need to look at ageing together with SARS-CoV-2 what are the genes at the intersection of these two pathways?

To select approved drugs that might act on these pathways, the team turned to big data and Artificial Intelligence (AI). The researchers narrowed the list of potential drugs by homing in on key genetic pathways, mapping the interactions of proteins involved in the ageing and SARS-CoV-2 infection pathways.

The team then identified areas of overlap among the two maps. That effort pinpointed the precise gene expression network that a drug would need to target to combat COVID-19 in elderly patients.

We want to identify a drug that has an effect on all of these differentially expressed genes downstream, says Belyaeva.

The team used algorithms that infer causality in interacting systems to turn their undirected network into a causal network. The final causal network identified RIPK1 as a target gene/protein for potential COVID-19 drugs since it has numerous downstream effects. The researchers identified a list of the approved drugs that act on RIPK1 and may have potential to treat the virus, including ribavirin and quinapril, which are already in clinical trials for COVID-19.

Im really excited that this platform can be more generally applied to other infections or diseases, says Belyaeva.

The team plans to share its findings with pharmaceutical companies.

Read the rest here:
Using machine learning to find COVID-19 treatment options - Health Europa

Scientists use machine learning to tackle a big challenge in gene therapy – STAT

As the world charges to vaccinate the population against the coronavirus, gene therapy developers are locked in a counterintuitive race. Instead of training the immune system to recognize and combat a virus, theyre trying to do the opposite: designing viruses the body has never seen, and cant fight back against.

Its OK, really: These are adeno-associated viruses, which are common and rarely cause symptoms. That makes them the perfect vehicle for gene therapies, which aim to treat hereditary conditions caused by a single faulty gene. But they introduce a unique challenge: Because these viruses already circulate widely, patients immune systems may recognize the engineered vectors and clobber them into submission before they can do their job.

Unlock this article by subscribing to STAT+ and enjoy your first 30 days free!

STAT+ is STAT's premium subscription service for in-depth biotech, pharma, policy, and life science coverage and analysis.Our award-winning team covers news on Wall Street, policy developments in Washington, early science breakthroughs and clinical trial results, and health care disruption in Silicon Valley and beyond.

View original post here:
Scientists use machine learning to tackle a big challenge in gene therapy - STAT

Machine Learning in Tax and Accounting Market gigantic revenues by 2028 with Amazon Web Services, Baidu Inc, Google, Intel, IBM, Hewlett Packard,…

Machine learning can help classify tax-sensitive transactions. Machine learning tax algorithms can be developed to search for and identify assets that are incorrectly booked into certain accounts by an organizations finance team, based on historical classifications your team has made.

When used as part of financial planning & analysis (FP&A), machine learning can be used to analyze data to define or refine data models used for forecasting. The quality of the data set being used and the risk of inherent biases may again impact the quality of the predictions provided by machine learning.

Combining AI with other technologies, such as robotic process automation, can allow accountants to redirect the time that they used to spend on mundane tasks toward performing high-value, high-impact tasks. Adding AI to accounting operations can also increase output quality by minimizing human errors.

Request for a sample report here @ https://www.reportconsultant.com/request_sample.php?id=44375

Major Players Covered in this Report:

Amazon Web Services, Inc.; Baidu Inc.; Google Inc.; H2O.ai; Intel Corporation; International Business Machines Corporation; Hewlett Packard Enterprise Development LP; Microsoft Corporation; SAS Institute Inc.; and SAP SE.

Report Consultant announced latest research on growth factors and development of Global Machine Learning in Tax and Accounting Market. A detailed study accumulated to offer latest insights about acute features of the Machine Learning in Tax and Accounting market. The report contains different market predictions related to market size, revenue, production, CAGR, Consumption, gross margin, price, and other substantial factors. While emphasizing the key driving and restraining forces for this market, the report also offers a complete study of the future trends and developments of the market. It also examines the role of the leading market players involved in the industry including their corporate overview, financial summary and SWOT analysis.

Machine Learning in Tax and Accounting Market Study assures you to advise higher than your competition. With Structured tables and figures examining the Machine Learning in Tax and Accounting, the research document provides you a leading product, submarkets, revenue size and forecast to 2028.

The study report offers a comprehensive analysis of Machine Learning in Tax and Accounting market size across the globe as regional and country level market size analysis, CAGR estimation of market growth during the forecast period, revenue, key drivers, competitive background and sales analysis of the payers. Along with that, the report explains the major challenges and risks to face in the forecast period.

Market segmentation by Vertical:

Market segmentation by regions:

The research report of the Machine Learning in Tax and Accounting market offers broad analysis about the industry on the basis of different key segments. Moreover, the research report presents a comprehensive analysis about the opportunities, new products, and technological innovations in the market for the players.

Additionally, the research report on Machine Learning in Tax and Accounting market provides an in depth analysis about market status, market size, revenue share, industry development trends, products advantages and disadvantages of the enterprise, enterprise competition pattern, industrial policy and regional industrial layout characteristics. Thus the study report offers a comprehensive analysis of market size across the globe as regional and country level market size analysis, estimation of market growth during the forecast period.

Get upto 40% Discount available on this Report @ https://www.reportconsultant.com/ask_for_discount.php?id=44375

This study also covers company profiling, specifications and product picture, sales, market share and contact information of various regional, international and local vendors of Global Machine Learning in Tax and Accounting Market. The market opposition is frequently developing greater with the rise in scientific innovation and M&A activities in the industry. Additionally, many local and regional vendors are offering specific application products for varied end-users. The new merchant applicants in the market are finding it hard to compete with the international vendors based on reliability, quality and modernism in technology.

Detailed TOC of Machine Learning in Tax and Accounting Market Research Report-

Machine Learning in Tax and Accounting Introduction and Market Overview

Machine Learning in Tax and Accounting Market, by Application

Machine Learning in Tax and Accounting Industry Chain Analysis

Machine Learning in Tax and Accounting Market, by Type

Industry Manufacture, Consumption, Export, Import by Regions

Industry Value ($) by Region

Machine Learning in Tax and Accounting Market Status and SWOT Analysis by Regions

Major Region of Machine Learning in Tax and Accounting Market

Major Companies List

Conclusion

About Us:

Report Consultant A worldwide pacesetter in analytics, research and advisory that can assist you to renovate your business and modify your approach. With us, you will learn to take decisions intrepidly by taking calculative risks leading to lucrative business in the ever-changing market. We make sense of drawbacks, opportunities, circumstances, estimations and information using our experienced skills and verified methodologies.

Our research reports will give you the most realistic and incomparable experience of revolutionary market solutions. We have effectively steered business all over the world through our market research reports with our predictive nature and are exceptionally positioned to lead digital transformations. Thus, we craft greater value for clients by presenting progressive opportunities in the global futuristic market.

Contact us:

Riaana Singh

(Report Consultant)

sales@reportconsultant.com

http://www.reportconsultant.com

See the original post here:
Machine Learning in Tax and Accounting Market gigantic revenues by 2028 with Amazon Web Services, Baidu Inc, Google, Intel, IBM, Hewlett Packard,...

Using AI and Machine Learning will increase in horti industry – hortidaily.com

The expectation is that in 2021, artificial intelligence and machine learning technologies will continue to become more mainstream. Businesses that havent traditionally viewed themselves as candidates for AI applications will embrace these technologies.

A great story of machine learning being used in an industry that is not known for its technology investments is the story of Makoto Koike. Using Googles TensorFlow, Makoto initially developed a cucumber sorting system using pictures that he took of the cucumbers. With that small step, a machine learning cucumber sorting system was born.

Getting started with AI and machine learning is becoming increasingly accessible for organizations of all sizes. Technology-as-a-service companies including Microsoft, AWS and Google all have offerings that will get most organizations started on their AI and machine learning journeys. These technologies can be used to automate and streamline manual business processes that have historically been resource-intensive.

An article on forbes.com claims that, as business leaders continue to refine their processes to support the new normal of the Covid-19 pandemic, they should be considering where these technologies might help reduce manual, resource-intensive or paper-based processes. Any manual process should be fair game for review for automation possibilities.

Photo source: Dreamstime.com

Read the original:
Using AI and Machine Learning will increase in horti industry - hortidaily.com