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GCC is the GNU project's free and open-source cross-platform compiler collection. Now an anonymous reader shared this announcement from the mailing list for GCC: The GCC Steering Committee has decided to adopt a Code of Conduct for interactions in GCC project spaces, including mailing lists, bugzilla, and IRC.

The vast majority of the time, the GCC community is a very civil, cooperative space. On the rare occasions that it isn't, it's helpful to have something to point to to remind people of our expectations. It's also good for newcomers to have something to refer to, for both how they are expected to conduct themselves and how they can expect to be treated...

At this time the CoC is preliminary: the code itself should be considered active, but the CoC committee (and so the reporting and response procedures) are not yet in place. There's also an official FAQ, and GCC's Code of Conduct begins with this introduction. "Like the free software community as a whole, the GCC community is made up of a mixture of professionals and volunteers from all over the world, working on every aspect of the project including mentorship, teaching, and connecting people."

Where this leads to issues and unhappiness, "we have a few ground rules that we ask people to adhere to... [T]ake it in the spirit in which it's intended a guide to make it easier to enrich all of us, the project, and the broader communities in which we participate."

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GCC Steering Committee Announces a Code of Conduct - Slashdot

June 29, 2023 | Illumina announces an AI algorithm that predicts disease-causing genetic mutations; American Gene Technologies new company will focus solely on advancing an HIV cure; Datacubed looks for genomic foundation for PTSD; and new partnerships for NTT Research, the National Cerebral and Cardiovascular Center, Seqera Labs, Genomics England, Complete Genomics. Plus, product updates from 10x Genomics, Thermo Fisher, Benchling, Saama Revvity, and more.

Illumina Ventures is launching Illumina Ventures Labs, which will operate and provide access to fully equipped genomics labs in the US and the UK, mentorship, and seed financing to attract a broad range of genomics related start-ups. Illumina, Inc. will provide the start-ups with technical guidance from its subject matter experts and will provide Illumina Ventures Labs access to its next-generation sequencing (NGS) platforms, in lieu of operating its Accelerator program. Press release.

Insilico Medicine announced that it has completed the first dose in patients in the Phase II clinical trial of INS018_055, marking the world's first anti-fibrotic small molecule inhibitor discovered and designed using generative AI, initiating Phase II clinical trials for further evaluation. Press release.

The Max Delbrck Center in Berlin and Heidelberg University founded a new Helmholtz Institute for Translational AngioCardioScience (HI-TAC) in Mannheim and Heidelberg, Germany. The institute will integrate vascular biomedicine, systems biology and heart research. Establishment of HI-TAC will begin in July 2023. The project will benefit from partnerships with the European Center for Angioscience (ECAS) at the University Medical Center Mannheim, the Department of Cardiology and Institute of Experimental Cardiology at Heidelberg University Hospital, the Berlin Institute of Health at Charit (BIH), Charit Universittsmedizin Berlin, and the German Center for Cardiovascular Research (DZHK). Press release.

Bio-Techne Corporation has reached an agreement to acquire Lunaphore, Inc. Bio-Techne anticipates the acquisition to close in the first quarter of its fiscal 2024. Lunaphore is a leading developer of fully automated spatial biology solutions using precision microfluidic technology capable of revealing hyperplex proteomic and transcriptomic biomarkers in tumors and other tissues at single-cell and subcellular resolution. Lunaphore's spatial biology technology enables the identification of biomarker "signatures" with clinical relevance, providing data necessary to support the development of diagnostic tools and streamline clinical trials, and ultimately improve patient outcomes. Bio-Techne and Lunaphore recently announced a strategic partnership to develop the first fully automated spatial multiomic workflow. Press release.

SandboxAQ announced its bio-pharma molecular simulation division, AQBioSim. The division is helping biopharma and research institutions achieve breakthroughs in treatments for cancer, Alzheimers, Parkinsons, and other conditions. The company is currently working with a range of biopharma companies and university research labs, including AstraZeneca, Sanofi, and UC San Francisco. Initial customer milestones show that these technologies can decrease the time and cost of developing new therapies, and de-risk drug portfolios before entering preclinical and clinical stages. These tools serve as the catalyst for a suite of drug discovery solutions that combine the accuracy of quantum mechanical equations with the speed and power of AI, available on classical computing hardware. Subsequent advancements include large-scale molecular dynamics simulations able to handle complex, undruggable targets. Press release.

Neogap Therapeutics announced its acquisition of the remaining 30% of the shares in its subsidiary, TCER Oncology AB. This acquisition will broaden Neogap's patent portfolio and strengthen the company's pipeline of potential drug candidates, further consolidating Neogap's position in the field. The acquisition not only expands Neogap's patent portfolio but also enhances the company's pipeline of potential candidates for future preclinical and clinical development. Press release.

Saama has launched its unified platform of SaaS-based products to accompany its existing portfolio of customized solutions and services. The Saama platform deploys its artificial intelligence (AI)- and machine learning (ML)-enhanced solutions to automate key clinical development processes and provide a holistic view of trial operations and patient progress in one location. By applying AI and advanced analytics to key clinical development processes, Saamas platform eliminates manual, resource-intensive activities, allowing life science organizations to optimize productivity as well as gain deeper insights into patients behaviors and their real-time response to treatments. Press release.

Culture Biosciences and Cytiva are collaborating to advance innovation in upstream bioprocessing by providing customers greater access to predictive and robust scale-up capabilities. Together, Cytiva and Culture Biosciences aim to bring to customers new bioprocess solutions that use digitization, in-silico approaches, and virtual monitoring and control of experiments. Cytivas Bioreactor Scaler tool now includes Cultures 250 mL bioreactor. The Bioreactor Scaler tool enables seamless scaling between development and manufacturing. Scientists can identify scale-up or scale-down process control parameters by entering in their existing process details and cell line characteristics. The tool helps to de-risk scaling activities and ensure product quality. Teams can collaborate virtually from anywhere. Press release.

Datacubed Health is partnering with Eugene Lipov, M.D. in a pioneering study focused on the extent of physiologic impact of post-traumatic stress on the body including impact on the DNA of the patient. This research, sponsored by ErasePTSD Now, The Donovan & Bank Foundation, and Glenn Greenberg and Linda Vester Foundation, is specifically designed to evaluate and possibly reverse increased inflammation, reduced testosterone levels, and accelerated aging known to occur due to extreme combat stress experienced by the U.S. special forces. The study will follow veterans who have served in special forces units. By applying Dual Sympathetic Reset, the study aims to provide significant relief to participants and potentially transform their lives mentally as well as physically. The outcomes of this study have the potential to revolutionize the landscape of post-traumatic stress treatment for special forces combat veterans and enhance the well-being of countless individuals worldwide. Press release.

Complete Genomics announced new partnerships among other announcements for its 18th anniversary. Complete Genomics is partnering with Invivoscribe, a San Diego based-vertically-integrated biotechnology company, that will develop biomarker tests on DNBSEQ-G99RS platforms for oncology and cancer research. Complete Genomics also announced a pairing of its sequencing platform DNBSEQ-T7RS with AccuraGens proprietary assay technology. Press release.

The Pistoia Alliance announced a new partnership with Matador Japan KK to enable pre-competitive collaboration in the Japanese market. Pistoia and Matador share the vision that bringing together experts from diverse backgrounds and experiences will enable companies to deploy new technologies and solve common R&D challenges faster and more effectively. By joining forces, they will help members accelerate research and grant them access to a truly global pharmaceutical ecosystem. Together, Pistoia and Matador will create further networking and interest groups in the Japanese language and time-zone that directly benefit member organizations in the region. Japanese pharmaceutical companies have demonstrated R&D excellence in areas such as targeted immunotherapy, the human microbiome, and neurology. Partnering with the Pistoia Alliance will give members access to global expertise in these domains. Press release.

Pixelgen Technologies has commercially launched its first kit, the Pixelgen Single Cell Spatial Proteomics Kit, Immunology Panel I, Human (Pixelgen SCSP Kit), which is based on the company's proprietary Molecular Pixelation (MPX) technology for spatial analyses of immune cell surface proteins in 3D. The Pixelgen Single Cell Spatial Proteomics Kit, Immunology Panel I, Human (Pixelgen SCSP Kit) is the first product to convey spatial polarization and colocalization of proteins on the cell surface at high-multiplex, in 3D, offering new insights into biology in health and disease. The new kit includes commercial protocol, reagents, and free software to perform and analyze Molecular Pixelation in single cells. The Pixelgen SCSP Kit aims to close those gaps by capturing 3D maps of how proteins are spatially organized on the cell surface and in relation to one another. Press release.

SomaLogic and Citogen, the Longwood Groups customer services and support unit, are collaborating to establish SomaLogics first authorized site in Spain. As part of the agreement, Citogen will offer the 7,000-plex SomaScan Assay and provide SomaScan data to their customers in Southern Europe supporting biological research across an array of disciplines including clinical research, population health studies and nutrigenomics. Press release.

BC Platforms announced the addition of one of Brazils leading cardiology centers, Hospital do Corao (HCor), to its Global Data Partner Network, BCRQUEST.COM, to drive insights into drug discovery and development through analytics and realize the potential of real-world data worldwide. HCor possesses valuable longitudinal patient data, including on cardiovascular conditions such as atrial fibrillation, heart failure, and stroke. Today, BCRQUEST.COM holds rich real-world data from more than 65 million patient lives on 6 continents including North America, South America, Europe, Africa, Asia and Australia. Since 2021, HCor has made significant strides in digitalization by implementing an electronic medical records system and integrating technology across various sectors of its operations. Press release.

Revvity has launched Signals Research Suite, a unified, cloud-native SaaS platform that drives scientific collaboration across R&D disciplines from drug discovery to specialty chemicals material development. The new solution from Revvity Signals Software, the software and informatics arm of Revvity, is available worldwide. It integrates the Revvity Signals Notebook, VitroVivo and Inventa applications into a single, robust solution that supports the entire drug development process, from early research and in vitro testing and safety to early development as well as specialty chemicals new product development. Press release.

American Gene Technologies (AGT) launched a new companyAddimmuneto continue to develop gene and cell therapy technologies to cure HIV. Addimmune will focus solely on advancing an HIV cure, building upon more than a decade of work by AGT that led to a successful Phase 1 HIV gene and cell therapy clinical trial. Addimmune aims to create tremendous benefits for HIV patients, payers, and the public. Its gene therapy technology has the power to transform millions of lives. The new companys name represents a fusion of two fundamental concepts: using gene and cell therapy to add new capacity to the human T cell to create an improved immune system to fight HIV. Press release.

NTT Research and the National Cerebral and Cardiovascular Center (NCVC) are jointly launching a Bio Digital Twin Center in Suita, Japan. This initiative extends and expands the scope of a joint agreement on cardiovascular bio digital twin (CV BioDT) research between the two organizations reached in 2020. Scientists at the NTTR-NCVC Bio Digital Twin Center intend to create applications by integrating mathematical models, co-developed by the MEI Lab and NCVC, onto the CV BioDT platform advanced by the MEI Lab. Drs. Kazunori Uemura and Keita Saku (M.D., Ph.D.s) will lead the NTTR-NCVC Bio Digital Twin Center, respectively, as laboratory chief and acting director. This is the NCVCs first such collaboration with a company partner. Press release.

Parse Biosciences launched CRISPR Detect, enabling single cell pooled CRISPR screens at unprecedented scale. Bulk pooled CRISPR screening has been a valuable tool to understand gene function on a genome scale. Adding single cell resolution to pooled CRISPR screens pairs individual gene perturbations with rich whole transcriptome expression phenotypes. CRISPR Detect brings the scale of existing Parse Evercode technology to single cell CRISPR screening by enabling users to pair perturbations and transcriptional profiles in up to one million cells in a single experiment. This scale will expand the applications of single cell CRISPR screening particularly in drug discovery where cost has limited their use to targeted validation studies. Press release.

Cima University of Navarra and the Weizmann Institute of Science have signed an agreement for research against cancer. This agreement aims to implement three pioneering biomedical projects that combine artificial intelligence, cutting-edge genetic technology, and advanced therapies. These projects seek to improve the treatment of lung and pancreatic cancer, two of the most lethal types of tumors, and multiple myeloma, the second most common blood cancer. Press release.

Benchling launched new integrations and features that connect data and analytics tools directly in Benchling with just a few clicks, providing scientists with a connected platform to make faster decisions and generate better insights. Scientists now have out-of-the-box integrations to leading scientific analytics tools like JMP as well as Pluto and Watershed delivering effortless push and pull of data, results, and charts between Benchling and these solutions, along with API endpoints for developers to build their own analytics integrations. Press release.

Waters Corporation and Sartorius are collaborating to develop integrated analytical solutions for downstream biomanufacturing, expanding their joint agreement that began with upstream bioprocessing analytics. Software and hardware integrations between the Waters PATROL UltraPerformance Liquid Chromatography (UPLC) Process Analysis System and the Sartorius Resolute BioSMB multi-column chromatography platform will give bioprocess engineers access to more comprehensive analytical data for downstream batch and continuous manufacturing, improving yields while reducing waste and driving down biomanufacturing costs. Press release.

Thermo Fisher Scientific unveiled the Thermo Scientific Orbitrap Astral mass spectrometer. The new Astral analyzer combines fast throughput, high sensitivity and deep proteome coverage to allow researchers worldwide to uncover proteins that previously evaded detection and make breakthrough discoveries more efficiently than ever. Researchers can use this information to identify new clinical biomarkers, reveal diseases earlier and develop new interventions for everything from cardiovascular disease to cancer. Press release.

Neogap Therapeuticss patent application for the European market is being prepared for approval through a Notice of Allowance. Neogap has now obtained final approval from the European Patent Office for their pioneering approach to multiplying T-cells outside the body using their EpiTCer technology and the production of tumour-specific T-cells. The patent, valid until 2038, ensures that Neogaps EpiTCer technology is patent protected across various markets. Press release.

Avacta Group PLC has acquired Coris Bioconcept SRL for an upfront cash consideration of 7.4 million (on a debt-free/cash-free basis and subject to customary working capital adjustments), with an earnout based on future business performance, payable in cash, of up to 3.0 million. Coris, based in Gembloux, Belgium, and established in 1996, develops, manufactures, and markets rapid diagnostic test kits, mainly lateral flow tests, for use by healthcare professionals. Coris is ISO 13485 certified and markets its products through distributors in Europe, Asia, South America, Africa and Oceania. Coris product portfolio comprises diagnostic tests for respiratory, gastro-enteric and blood-borne pathogens (bacteria, viruses and parasites) and for the detection of antibiotic resistance markers. As part of this portfolio, Coris markets a COVID-19 lateral flow test. Avacta has taken the commercial decision to halt the redevelopment of its own AffiDX SARS-CoV-2 antigen lateral flow test. Press release.

Illumina announced the new PrimateAI-3D, an artificial intelligence (AI) algorithm that predicts with unprecedented accuracy disease-causing genetic mutations in patients. The results are published in two papers in the June 2 issue of Science, detailing the training of the algorithm and its application to half a million genomes in the UK Biobank cohort. Two accompanying papers on the primate evolution research that informed the development of PrimateAI-3D also published in the journal today. Press release.

Wheeler Bio and Charles River Laboratories announced an agreement to implement RightSourceSM at Wheeler Bios current good manufacturing practice (cGMP) biologics manufacturing facility in Oklahoma City, OK. Deployed on-site at a clients facility, RightSourceSM is a flexible biologics testing lab operated and managed by Charles River, making fast, reliable quality control (QC) more accessible to a broader reach of companies like Wheeler Bio. Wheeler Bio and Charles River will work in close collaboration to set up a cGMP testing lab at Wheeler Bios ultra-modern Oklahoma City facility. This platform-based satellite lab will be operated by Charles River employees who will utilize Charles Rivers quality management systems, test methods, and standard operating procedures (SOPs) to support all QC testing needs for Wheeler Bio. Press release.

Mission Bio announced breakthrough improvements to the Tapestri Platform and its core chemistry that enable highly confident detection of rare cells for a range of applications. With Tapestri v3 chemistry, researchers can discover tiny numbers of single cells that, until now, easily escaped detection and influenced disease in invisible ways. At the same time, drug developers can use the new capabilities for a more complete understanding of their advanced therapies, potentially leading to safer, more effective medicines. Tapestris new capabilities also hold promise for cell and gene therapy developers looking to improve quality assessment throughout the therapy development process. Press release.

Speedata announced the results of a simulation of its Analytics Processing Unit (APU) on a compound similarity analysis workload in the pharmaceutical industry. Using the APU, the analysis was completed in 19 minutes, compared to 90 hours when using a CPUa 280x faster result. Speedata's APU alleviates the main bottlenecks of data analytics, significantly improving the speed and performance when analyzing such workloads, dramatically reducing costs and increasing efficiency. The APU's unique architecture is compatible with all legacy software, allowing for seamless migration of workloads, with no changes necessary to an enterprise's code or existing framework. Press release.

Seqera Labs has partnered with Genomics England. The new collaboration between Seqera Labs and Genomics England will enable whole genome analysis to be carried out at a larger scale with greater efficiency, helping more patients benefit from genomic healthcare and equipping researchers with extra data to find the causes of disease and develop new treatments. The partnership with Seqera Labs will scale Genomics Englands capacity to develop models for disease diagnosis, prognosis and treatment response. Genomics England will deploy Seqera Labs Nextflow Tower, an intuitive, centralised command post that enables large-scale collaborative data analysis. With Tower, Genomics England will be able to quickly launch, manage, and monitor scalable data analysis pipelines within the cloud. Press release.

10x Genomics announced the commercial availability of a new Visium CytAssist Gene and Protein Expression product to expand the breadth of the Visium CytAssist spatial analysis capabilities. Visium CytAssist Gene and Protein Expression enables researchers to simultaneously produce highly multiplexed protein and whole transcriptome RNA data mapped together from the same formalin-fixed, paraffin-embedded (FFPE) tissue section at high spatial resolution. Press release.

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AI Predicts Diseases, Advancing Toward HIV Cure, Acquisitions ... - Bio-IT World

WISeKey has unveiled a major upgrade to its digital identity and privacy platform, WISeID.com, designed to provide users with enhanced protection against identity theft and increase privacy in todays hyper-connected digital world.

The new generation of WISeID builds upon WISeKeys tradition of pioneering advanced cybersecurity solutions and introduces a suite of significant improvements to further secure users digital identities and personal data.

New free identity validation: Now all WISeID users can verify their real identity using the computer or phone webcam to capture an identity document (National ID, Driver License, or Passports of most countries are accepted) and do face recognition.

New types of certificates: users can now get digital certificates with different validation levels:

New document signature service: WISeID users now benefit of a free document signature solution. Users can simply sign a PDF document from their computer or mobile, without having to worry about creating and installing certificates in their devices. Our platform generates automatically, and securely single-use certificates whenever is needed to sign a document. The person that signs up can do it for free, and the only requirement is to have a valid WISeID Account and validate their identity.

New corporate service: Companies willing to provide WISeID services to employees or customers can get a corporate account, which gives administrative access to create users and manage their certificates. Corporate users dont need to do individual identity verification. Corporate customers can also get WISeSign packages that can be shared by all the users to request signatures.

Our goal is to make available our new security services to all WISeID users, said Pedro Fuentes, WISeKeys Trust Services Manager. This latest update is a leap forward in that mission. We have strengthened our existing free features and added new premium services that will allow users to protect their digital life.

Privacy is at the core of the new WISeID. Users now have increased control over their personal information, choosing who they share it with and when. Furthermore, an innovative data anonymization feature ensures user activities cannot be traced back to them, further safeguarding their privacy.

We have always believed in the power of technology to protect and empower individuals in the digital realm. With the new WISeID, we are taking another step in ensuring our users can enjoy the benefits of digital connectivity without compromising their privacy or falling prey to identity theft, Fuentes concluded.

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WISeKey upgrades its WISeID digital identity and privacy platform - Help Net Security

According to NBC News, the FBI created a national online database in May to facilitate information sharing between hundreds of police departments and law enforcement agencies across the country pertaining to swatting incidents. From the report: No central agency has tracked swatting incidents or suspects in the U.S., so official statistics are not available. By 2019, there were an estimated 1,000 swatting incidents domestically each year, according to a report from the Anti-Defamation League, and each incident is estimated to cost at least $10,000 to affected communities, even before expenditures on follow-up work like investigations, property repairs and counseling. Swatting is increasingly enabled by technology that can be used to mask a caller's real voice, their phone number or IP address (also called "spoofing") or to make their false report sound more credible.

[Chief Scott Schubert with the bureau's Criminal Justice Information Services headquarters in Clarksburg, West Virginia] told NBC News that the FBI's new centralized database should help the agency "get that common picture of what's going on across our nation so we can learn from that." [...] While the earliest recorded case of swatting occurred in 2002, to this day, there is no specific law criminalizing swatting in the U.S., says John Jay's Shapiro. "Without a statute in place, there's no designated resources or training for investigating swatting incidents," she said. "And the 911 dispatchers do not have the resources and training they need to differentiate between actual emergencies and false reports."

Legally, the False Information and Hoaxes statute, also known as section 1038, is most frequently used to prosecute swatting. Other statutes can sometimes apply -- one pertaining to interstate threats involving explosives and another pertaining to interstate communications, which refers to extortion or threats to injure or kidnap somebody. "Too often, perpetrators are getting a slap on the wrist compared to the consequences suffered by their victims," Shapiro said.

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FBI Forms National Database To Track and Prevent 'Swatting' - Slashdot

The Software Training Lab in the Harold B. Lee Library provides free classes for BYU students, faculty and staff to learn to use various software programs.

Programs offered include Adobe Creative products, Microsoft Office and other software like Procreate and DaVinci Resolve. Through the program, students learn the basics of how to operate each program and create a project to showcase their knowledge. Prior experience in a program is not required to take any of the classes, according to Henry Sorensen, outreach lead for the Software Training Lab.

While these classes do not count toward class credit, they still provide students with valuable skills.

The real purpose behind it is that we want to get people experience and skills in these programs so that they can use them on their own, Sorensen said. We hope that when they come out of the class, theyll have learned something new, regardless of whether theyre a novice or an experienced user of the program.

The lab teaches classes each semester or term and has offered the classes for at least a decade, according to Sorensen. He said the lab tries to continue classes that were popular in previous semesters and vary the time of classes each semester to accommodate student schedules. The classes have a specific curriculum which is revamped every couple of years to keep up with updating software and materials.

Lee Martin, software training desk lead, said some classes are staples, such as Adobe Photoshop and Illustrator, but the lab has even done classes about YouTube and is developing a podcasting class.

Courses are usually around six hours total, which is broken up into several classes over a couple weeks, so they are a fairly low time commitment, Sorensen said. The library provides patrons with access to the software programs and computers necessary both during and outside of classes. There is also a help desk for patrons, so those who are having trouble with programs can get one-on-one help.

One goal of the classes is to help build community and connect students with others who are in the same creative mindset, according to Martin. There are collaborative activities in the classes to encourage students to work with each other.

Soren Patchell enrolled in software classes because she is considering applying to the advertising program in the BYU School of Communications. Patchell said the Adobe software is a skill set many teach themselves. She felt she was behind other advertising students because she never tried it in high school and does not have much experience.

I already feel like its helped so much because I honestly didnt know anything going into it. I think just doing this step by step has really helped me because I wouldnt even know where to start other than YouTube, Patchell said.

Patchell wants to continue to take classes, including using Lightroom and Photoshop.

According to Sorensen, it is usually BYU students who take the classes, although during spring and summer terms it is more common to see faculty and staff take the classes as well.

The classes are not offered to members of the community, but Martin said if someone is affiliated with a BYU student, staff or faculty member, they could sign up with that person to join a class.

That was the case for Staci Blackmon, who was able to attend the software classes because she had a net ID from attending BYUIdaho and her sister is a current BYU student. Blackmon said she is currently living in Provo while job searching and is not attending school, so when she saw the classes on the BYU calendar she thought it would be a great opportunity to learn the skills for free without having to teach herself.

Blackmon said she brings her own computer and uses a mobile hotspot since she is unable to access the computers and Wi-Fi as she is not a current BYU student, but she makes it work. She just started the InDesign course and has also taken courses in Photoshop, Illustrator and Excel.

I love learning the keyboard shortcuts, best part of any program. And the creativity that it encourages, while still having limits. Because I cant just go off on my own, I need help, Blackmon said.

Another benefit to the classes is that, in connection with the Instructional Psychology and Technology Department, the lab offers badges to students that they can put on a resume to show the projects they have worked on and the certification they earned from the class, Sorensen said.

According to Martin, even without taking the classes, badges are offered to anyone who can show they have the skills to operate the program.

Blackmon started the work toward the badges and plans on submitting them after she wraps up the classes she is currently taking and finishes her projects.

Interested parties can register for classes on the librarys Software Training Lab website.

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BYU Library offers free software classes - The Daily Universe - Universe.byu.edu