Archive for May, 2020

25 Million Students On COVID-19: Depression, Anxiety And Loneliness Hitting Peak Levels – Forbes

20% of college students are more depressed.

11% are more anxious.

16% are more lonely.

A college student studying, surrounded by books.

COVID-19 has caused serious emotional challenges for young people. In fact, according to Wisdo, a peer-to-peer counseling community, pandemic anxiety is almost three times more worrying to this age group than any other stress-creating experiences pre COVID-19.

Three-time bestselling New York Times author Dan Ariely, who wrote Predictably Irrational and is a professor of psychology and behavioral economics at Duke University, uses the app and is an advisor to the company. He says the virus is a huge issue, and the economic impact of shutdowns is massive.

But most important is the psychological impact.

Theres lots of things happening in this Corona crisis, but one of them is the unpredictability of the world, and the reality that when things are unpredictable theyre very hard to deal with, Ariely told me on the TechFirst podcast. And who has the most amount of unpredictability? Young people ... they basically have no control over their environment.

When the world is unpredictable and bad things happen, learned helplessness sets in, Ariely says.

Stress builds as well: health and medical stress, financial stress, even stress from being in close proximity for a long time with the same people during shutdown. These are all results of schools shutting down, jobs being lost, and college students uncertainty of when and how they will be able to resume classes and move towards careers.

Wisdo is conducting what it calls the worlds first comprehensive study of mental health during the pandemic. The study will encompass all users of the app in the U.S. and the UK and will last through the entire 2020 year.

The initial findings are not good.

Dan Ariely

Depression, anxiety, and stress are leading to sleeping problems, trouble expressing thoughts and feelings in conversation, and challenges with enjoying life. And theres been a huge increase in the number of students reporting excessive worrying.

Ariely isnt just speaking theoretically or academically about how a lack of control of your circumstances impacts your wellness and mental health. Hes experienced what hes talking about and its why he wears half a beard.

I was burned 70%, I was in hospital for about three years, he told me. The lack of knowledge of whats going to happen and not being able to control my own destiny in any way was incredibly tough ... it was incredibly psychologically challenging.

So what can students or adults who have lost a job do to regain a sense of control and some level of mental health?

Ariely says there are some simple steps anyone can take.

Were not going to get a lot of control back, Ariely says. The question is, can we get some of it back? And so in hospital, one way to give people control is whats called patient controlled analgesia when you basically have a button and you decide when to press and that gives you medication on your time.

The key, Ariely says, is to find something like that in our lives. Something that provides some level of control, and shows quick results. Examples that most of us are seeing on social media probably include baking bread especially sourdough or hobbies like knitting or art. Retail therapy is another, Ariely says, but he doesnt recommend it. (Gets expensive, he says.)

Essentially, anything that shows you quick improvement is best.

Corona time is giving us an opportunity to work on those things, and this is a sense of control, Ariely says. Why? Because its a process that allows you to see progress. If you start to meditate, it gives you progress. Another, a good thing to do is to do push ups. Why? You could see the increase, right? First day its maybe three and then you can move at some to four, but what you want is things that you can actually see the improvement.

And that sourdough were seeing on social media?

Its the modern-day Tamagotchi, says Ariely. Keeping something alive even some yeast is an exercise in creativity and control that can help us feel better in general.

See the full transcript of our conversation here.

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25 Million Students On COVID-19: Depression, Anxiety And Loneliness Hitting Peak Levels - Forbes

Julia Roberts, Hugh Jackman, & More to Hand Over Social Media Accounts to COVID-19 Experts – Just Jared

Julia Roberts and Hugh Jackman are giving up control of their social media accounts!

Starting on Thursday (May 21), stars will be handing over their social accounts to COVID-19 experts as part of the #PassTheMic campaign.

Experts including Dr. Anthony Fauci will use the stars platforms to share facts and science-driven perspectives on the pandemic. The campaign will continue for several weeks and feature frontline workers as well as health, economic, and other experts.

Other stars that will be taking part in the campaign include Shailene Woodley, Danai Gurira, Millie Bobby Brown, Penelope Cruz, Rainn Wilson, Rita Wilson, David Oyelowo, Connie Britton, and Sarah Jessica Parker.

Beating the virus means listening to the experts and following the science, data and facts to get ahead of it. This impressive group of talent and experts from around the world will put a spotlight on the need for a global response to this pandemic, ONE Campaign President and CEO, Gayle Smith said in a statement. We need global cooperation and action to fight this pandemic especially for the people, communities, and countries that are least able to withstand the shock. Because none of us are safe until all of us are safe.

You can head to Pass the Mic for a full list of celebrities and experts that will be participating in the campaign.

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Julia Roberts, Hugh Jackman, & More to Hand Over Social Media Accounts to COVID-19 Experts - Just Jared

Insidious Android malware gives up all malicious features but one to gain stealth – We Live Security

ESET researchers detect a new way of misusing Accessibility Service, the Achilles heel of Android security

ESET researchers have analyzed an extremely dangerous Android app that can perform a host of nefarious actions, notably wiping out the victims bank account or cryptocurrency wallet and taking over their email or social media accounts. Called DEFENSOR ID, the banking trojan was available on Google Play at the time of the analysis. The app is fitted with standard information-stealing capabilities; however, this banker is exceptionally insidious in that after installation it requires a single action from the victim enable Androids Accessibility Service to fully unleash the apps malicious functionality.

The DEFENSOR ID app made it onto the heavily guarded Google Play store thanks to its extreme stealth. Its creators reduced the apps malicious surface to the bare minimum by removing all potentially malicious functionalities but one: abusing Accessibility Service.

Accessibility Service is long known to be the Achilles heel of the Android operating system. Security solutions can detect it in countless combinations with other suspicious permissions and functions, or malicious functionalities but when faced with no additional functionality nor permission, all failed to trigger any alarm on DEFENSOR ID.

By all we mean all security mechanisms guarding the official Android app store (including the detection engines of the members of the App Defense Alliance) and all security vendors participating in the VirusTotal program (see Figure 1).

Figure 1. According to the VirusTotal service, no security vendor detected the DEFENSOR ID app until it was pulled off the Play store

DEFENSOR ID was released on Feb 3, 2020 and last updated to v1.4 on May 6, 2020. The latest version is analyzed here; we werent able to determine if the earlier versions were also malicious. According to its profile at Google Play (see Figure 2) the app reached a mere 10+ downloads. We reported it to Google on May 16, 2020 and since May 19, 2020 the app has no longer been available on Google Play.

The developer name used, GAS Brazil, suggests the criminals behind the app targeted Brazilian users. Apart from including the countrys name, the apps name is probably intended to imply a relationship with the antifraud solution named GAS Tecnologia. That security software is commonly installed on computers in Brazil as several banks require it to log into their online banking. However, there is also an English version of the DEFENSOR ID app (see Figure 3) besides the Portuguese one, and that app has neither geographical nor language restrictions.

Playing further off the suggested GAS Tecnologia link, the app promises better security for its users. The description in Portuguese promises more protection for the users applications, including end-to-end encryption. Deceptively, the app was listed in the Education section.

Figure 2. The DEFENSOR ID app on Google Play Portuguese version (translates roughly as: Your new Defensor app available for: / Individuals / Legal entities / From now on you will have more protection when using your applications, encryption for end-to-end users)

Figure 3. The DEFENSOR ID app on Google Play English version

After starting, DEFENSOR ID requests the following permissions:

If an unsuspecting user grants these permissions (see Figure 4), the trojan can read any text displayed in any app the user may launch and send it to the attackers. This means the attackers can steal the victims credentials for logging into apps, SMS and email messages, displayed cryptocurrency private keys, and even software-generated 2FA codes.

The fact the trojan can steal both the victims credentials and also can control their SMS messages and generated 2FA codes means DEFENSOR IDs operators can bypass two-factor authentication. This opens the door to, for example, fully controlling the victims bank account.

To make sure the trojan survives a device restart, it abuses already activated accessibility services that will launch the trojan right after start.

Figure 4. The permission requests by DEFENSOR ID

Our analysis shows the DEFENSOR ID trojan can execute 17 commands received from the attacker-controlled server such as uninstalling an app, launching an app and then performing any click/tap action controlled remotely by the attacker (see Figure 5).

Figure 5. The list of commands DEFENSOR ID may get from its C&C server

In 2018, we saw similar behavior, but all the click actions were hardcoded and suited only for the app of the attackers choice. In this case, the attacker can get the list of all installed apps and then remotely launch the victims app of their choice to either steal credentials or perform malicious actions (e.g. send funds via a wire transfer).

We believe that this is the reason the DEFENSOR ID trojan requests the user to allow Modify system settings. Subsequently, the malware will change the screen off time-out to 10 minutes. This means that, unless victims lock their devices via the hardware button, the timer provides plenty of time for the malware to remotely perform malicious, in-app operations.

If the device gets locked, the malware cant unlock it.

When we analyzed the sample, we realized that the malware operators left the remote database with some of the victims data freely accessible, without any authentication. The database contained the last activity performed on around 60 compromised devices. We found no other information stolen from the victims to be accessible.

Thanks to this data leak, we were able to confirm that the malware really worked as designed: the attacker had access to the victims entered credentials, displayed or written emails and messages, etc.

Once we reached the non-secured database, we were able to directly observe the apps malicious behavior. To illustrate the level of threat the DEFENSOR ID app posed, we performed three tests.

First, we launched a banking app and entered the credentials there. The credentials were immediately available in the leaky database see Figure 6.

Figure 6. The banking app test: the credentials as entered (left) and as available in the database (right)

Second, we wrote a test message in an email client. We saw the message uploaded to the attackers server within a second see Figure 7.

Figure 7. The email message test: the message as written (left) and as available in the database (right)

Third, we documented the trojan retrieving the Google Authenticator 2FA code.

Figure 8. The software generated 2FA code as it appeared on the devices display (left) and as available in the database (right)

Along with the malicious DEFENSOR ID app, another malicious app named Defensor Digital was discovered. Both apps shared the same C&C server, but we couldnt investigate the latter as it had already been removed from the Google Play store.

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Insidious Android malware gives up all malicious features but one to gain stealth - We Live Security

Inventiva secures a new patent for lanifibranor in China expanding the protection of its lead product candidate – GlobeNewswire

Daix (France), May 25, 2020 Inventiva (Euronext: IVA), a clinical-stage biopharmaceutical company developing oral small molecule therapies for the treatment of non-alcoholic steatohepatitis (NASH), mucopolysaccharidoses (MPS) and other diseases with significant unmet medical need, today announced that the China National Intellectual Property Administration (CNIPA) granted a new patent directed at the use of lanifibranor for the treatment of several fibrotic diseases in China until June 2035.

This new patent covers, among others, the use of the Companys lead product candidate lanifibranor for the treatment of NASH, hepatic fibrosis, chronic renal failure and fibrotic pulmonary disorder. It thereby expands the protection of the molecule in China, the worlds second largest market for the pharmaceutical industry1, and builds on a previously granted New Chemical Entity (NCE) patent.

Inventiva currently holds patents for lanifibranor in Asia, the United States and Europe.

Pierre Broqua, Ph.D., CSO and cofounder of Inventiva, said: "The granting of this patent is excellent news, expanding our protection of lanifibranor in several fibrotic diseases, including NASH, in China, and supports the innovative approach that we are pursuing in this treatment area. It also enables us to strengthen our positioning in regions where the need for treatment of fibrotic diseases is very high. This milestone builds on the significant progress achieved in our NASH program throughout 2019 and follows the last patient visit in our Phase IIb NATIVE clinical trial for which we are expecting the release of topline results next month.

About lanifibranor

Lanifibranor, Inventivas lead product candidate, is an orally-available small molecule that acts to induce anti-fibrotic, anti-inflammatory and beneficial vascular and metabolic changes in the body by activating all three peroxisome proliferatoractivated receptor (PPAR) isoforms, which are wellcharacterized nuclear receptor proteins that regulate gene expression. Lanifibranor is a PPAR agonist that is designed to target all three PPAR isoforms in a moderately potent manner, with a wellbalanced activation of PPAR and PPAR, and a partial activation of PPAR. While there are other PPAR agonists that target only one or two PPAR isoforms for activation, lanifibranor is the only panPPAR agonist in clinical development. Inventiva believes that lanifibranors moderate and balanced panPPAR binding profile contributes to the favorable safety and tolerability profile that has been observed in clinical trials and preclinical studies to date.

Inventiva is currently evaluating lanifibranor in a Phase IIb clinical trial for the treatment of NASH, a common and progressive chronic liver disease, for which there is currently no approved therapy.

About Inventiva

Inventiva is a clinical-stage biopharmaceutical company focused on the development of oral small molecule therapies for the treatment of NASH, MPS and other diseases with significant unmet medical need.

Leveraging its expertise and experience in the domain of compounds targeting nuclear receptors, transcription factors and epigenetic modulation, Inventiva is currently advancing two clinical candidates, as well as a deep pipeline of earlier stage programs.

Lanifibranor, its lead product candidate, is being developed for the treatment of patients with NASH, a common and progressive chronic liver disease. Inventiva is currently evaluating lanifibranor in a Phase IIb clinical trial for the treatment of this disease for which there are currently no approved therapies.

Inventiva is also developing odiparcil, a second clinical stage asset, for the treatment of patients with MPS, a group of rare genetic disorders. A Phase Ib/II clinical trial in children with MPS VI is currently under preparation following the release of positive results of the Phase IIa clinical trial in adult MPS VI patients at the end of 2019.

In parallel, Inventiva is in the process of selecting an oncology development candidate for its Hippo signalling pathway program. Furthermore, the Company has established a strategic collaboration with AbbVie in the area of autoimmune diseases. AbbVie has started the clinical development of ABBV157, a drug candidate for the treatment of moderate to severe psoriasis resulting from its collaboration with Inventiva. This collaboration enables Inventiva to receive milestone payments upon the achievement of pre-clinical, clinical, regulatory and commercial milestones, in addition to royalties on any approved products resulting from the collaboration.

The Company has a scientific team of approximately 70 people with deep expertise in the fields of biology, medicinal and computational chemistry, pharmacokinetics and pharmacology, as well as in clinical development. It also owns an extensive library of approximately 240,000 pharmacologically relevant molecules, approximately 60% of which are proprietary, as well as a whollyowned research and development facility.

Inventiva is a public company listed on compartment C of the regulated market of Euronext Paris (Euronext: IVA ISIN: FR0013233012). http://www.inventivapharma.com

Contacts

Inventiva

Frdric CrenChairman & CEOinfo@inventivapharma.com+33 3 80 44 75 00

Brunswick GroupYannick Tetzlaff / Tristan Roquet Montegon /Aude LepreuxMedia relationsinventiva@brunswickgroup.com+33 1 53 96 83 83

Westwicke, an ICR CompanyPatricia L. BankInvestor relationspatti.bank@westwicke.com +1415513 1284

Important notice

This press release contains forward-looking statements, forecasts and estimates with respect to Inventivas clinical trials, clinical development plans, and anticipated future activities of Inventiva. Certain of these statements, forecasts and estimates can be recognized by the use of words such as, without limitation, believes, anticipates, expects, intends, plans, seeks, estimates, may, will and continue and similar expressions. Such statements are not historical facts but rather are statements of future expectations and other forward-looking statements that are based on management's beliefs. These statements reflect such views and assumptions prevailing as of the date of the statements and involve known and unknown risks and uncertainties that could cause future results, performance or future events to differ materially from those expressed or implied in such statements. Actual events are difficult to predict and may depend upon factors that are beyond Inventiva's control. There can be no guarantees with respect to pipeline product candidates that the clinical trial results will be available on their anticipated timeline, that future clinical trials will be initiated as anticipated, or that candidates will receive the necessary regulatory approvals. Therefore, actual results may turn out to be materially different from the anticipated future results, performance or achievements expressed or implied by such statements, forecasts and estimates. Given these uncertainties, no representations are made as to the accuracy or fairness of such forward-looking statements, forecasts and estimates. Furthermore, forward-looking statements, forecasts and estimates only speak as of the date of this press release. Readers are cautioned not to place undue reliance on any of these forward-looking statements.

Please refer to the Universal Reference Document filed with the Autorit des Marchs Financiers on February 7, 2020 under n D.20-0038 for additional information in relation to such factors, risks and uncertainties.

Except as required by law, Inventiva has no intention and is under no obligation to update or review the forward-looking statements referred to above. Consequently, Inventiva accepts no liability for any consequences arising from the use of any of the above statements.

1 Market size measured in terms of sales. Source: IQVIA Institute: The Global Use of Medicine in 2019 and Outlook to 2023.

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Inventiva secures a new patent for lanifibranor in China expanding the protection of its lead product candidate - GlobeNewswire

Albert Einstein was right: we must democratize the UN – Democracy Without Borders

Three paths towards supranational democracy?

When I wrote Climate Change and the Future of Democracy in 2018, I discussed three distinct paths toward the goal of democratizing global governance in response to the climate crisis. The first path would bypass national governments altogether and organize municipalities on a global scale. This method was advocated by Benjamin Barber in his book If Mayors Ruled the World and has been further developed since his death in 2017 by the Global Parliament of Mayors. The second path would be to create a federal union of established democracies that could grow over time. The idea of combining the worlds democracies into a single federal union was advocated by Clarence Streit in his 1939 book Union Now, and the evolution of the European Union since the 1990s has made this strategy appear more plausible than it did during Streits lifetime. The third and most ambitious path toward supranational democracy would be to democratize the United Nations. The most famous advocate of this idea was the physicist Albert Einstein.

In an open letter to the UN General Assembly in October of 1947, Einstein declared that, The moral authority of the UN would be considerably enhanced if the delegates were directly elected by the people. Were they responsible to an electorate, they would have much more freedom to follow their consciences. Thus we could hope for more statesmen and fewer diplomats. At the time, critics in both the United States and the Soviet Union condemned Einsteins proposal, but the idea of bringing democratic representation to the United Nations has continued to grow over the past seventy-five years, and it has since been promoted by the Campaign for a UN Parliamentary Assembly.

The moral authority of the UN would be considerably enhanced if the delegates were directly elected by the people. (Einstein)

Each of these three paths toward supranational democracy has distinct advantages and drawbacks. Uniting municipal governments in a global parliament offers the advantage of bypassing nationalism, but it risks leaving rural people behind, which might exacerbate the cultural divisions between the city and countryside that have fueled the rise of illiberal politics around the world.

A federal union of democratic governments has a strong appeal since democracies have a long history of peaceful relations with each other, but it is bedeviled by the question of how it can balance political cohesiveness with democratic integrity when one of its member states elects to leave that federal union, or when one or more governments remaining within the union ceases to be a legitimate democracy.

Finally, the idea reforming the UN so that it includes an elected world parliament offers the compelling advantage of being the most direct and inclusive path toward supranational democracy, offering the possibility of representation to people in both rural and urban settings, and to people living under all forms of government. On the downside, this model is beset by the inevitable problem of unelected national governments sending handpicked delegates to the parliament who would not effectively represent the citizens of those countries. For this reason, a UN Parliamentary Assembly must remain an advisory body and must not attempt to consider any form of binding legislation until all of its representatives are elected in free and fair multi-party elections which are open to international monitoring.

A UN Parliamentary Assembly as most plausible response

In Climate Change and the Future of Democracy, I expressed qualified support for all of these approaches, and pointed out that they are not mutually exclusive. Nonetheless, I argued then that a federal union of established democracies was the steadiest path forward. Over the past two years, however, two developments have made the more ambitious goal of establishing a UN Parliamentary Assembly emerge as the most plausible response to the challenges we now face.

First, the process of backsliding in longstanding democracies has continued to accelerate, thus suggesting that any federal union of democracies would face an even more vexing choice between political cohesion and democratic integrity than that which confronts the European Union today. Second, the economic and political crisis engendered by the COVID-19 pandemic has brought the importance of agile and compassionate global governance to the forefront. This crisis, like the myriad ecological and public health crises that will emerge as a result of climate change in the near future, is global in nature and it requires a congruent response. If the UN is to meet this ongoing crisis and the others that lay just around the corner, it must become far more democratic, transparent, and responsive than it is today. The establishment of a UN Parliamentary Assembly is the necessary first step in that direction.

Unless we bring the responsiveness, adaptability, and accountability of democracy to the global regulation of trade and industry, we will not be able to deal with climate change and the myriad disasters and disruptions that it is bound to engender. If each democracy attempts to weather the coming storm in the service of its own national interest, none of them will survive, at least not in the form that we might honestly describe as a democracy. Such democratic principles as due process, privacy, freedom of the press, and free and fair elections have already been eroded in the twenty-first century, and they are not likely to survive in a world where extreme weather events, droughts, famines, and mass migrations are addressed by an anarchical society of sovereign nation states, each angling for its own advantage in a zero-sum game. Conversely,if wecan extend these vital principles of democracy beyond the nation-state, we will increase our own chances for survival through rational, accountable, and flexible cooperation.

Extending the principles of democracy beyond the nation-state will increase our chances of survival

The most difficult question regarding global democracy is not whether we should have it, but how we could possibly achieve it. The initiative in this case will not come from governments but from private citizens joining forces across national borders. The abolition of slavery in the nineteenth century and the political enfranchisement of women in the twentieth century both furnish excellent examples of how movements by individual citizens can lead to fundamental social, economic, and political change on a global scale. In his 2012essayThe State of the Speciesthe celebrated authorCharles Mann describes the scale of tremendous behavioral changes that have taken place in the past two centuries, includingthe statistical decline in violence documented by Harvard psychologistSteven Pinker,the near total eradication of slavery, and the growing enfranchisement of women across the world. Mann attributes these dramatic changes to the behavioral plasticity of human beings, a defining feature ofHomo sapiensbig brain.Citing more quotidian examples, Mann observes that this plasticity means that humans can change their habits; almost as a matter of course, people change careers, quit smoking or take up vegetarianism, convert to new religions, and migrate to distant lands where they must learn strange languages. While it is far from inevitable that we will change our collective behavior soon enough to avoid catastrophic climate change, Mann submits that it is at least a possibility.

Pointing to the vast human potential that has been liberated by social progress of thepast two centuries, Mann observes that, removing the shackles from women and slaves has begun to unleash the suppressed talents of two-thirds of the human race. Drastically reducing violence has prevented the waste of countless lives and staggering amounts of resources. He then poses the rhetorical question of whether we wouldnt use those talents and those resources to draw back before the abyss? Of course, the jury is still out on whether the past successes in human progress that Mann discusses portend future success in addressing the unprecedented challenge of climate change. However, Manns point about liberating the suppressed talents of two thirds of the human race suggests that supranational democracy is the political system is most likely to meet that challenge. The facts on the ground indicate that the protection of individual rights and access to education for women can pay dramatic dividends in fighting climate change. In his 2017 bookDrawdownthe environmentalistPaul Hawken reports that educating girls and women is the most powerful lever available for breaking the cycle of intergenerational poverty, while mitigating emissions by curbing population growth. Hawken also cites research that ranks campaign to educate girls, such as those led by Malala Yousafzai of Pakistan, as among the most cost-competitive options for reducing carbon dioxide emissions, requiring an approximate investment of just ten dollars per ton of carbon dioxide.

The slow and arduousexpansion of democracy and individual rights in the United States only began in earnestafter the catastrophe of the Civil War.In the years following of that conflagration, the American poetWalt Whitman penned an essay calledDemocratic Vistasin which he identified the creation of a universal community that honored each individual as the ultimate goal of democracy. This was a powerful ethos that ever seeks to bind, all nations, all men, of however various and distant lands, into a brotherhood, a family. Whitman identified this audacious goal as the old, yet ever-modern dream of earth, out of her eldest and her youngest, her fond philosophers and poets. Though Whitman viewed the horizontal expansion of democracy as encompassing the whole human race, he viewed the powers of any democratic government as limited by a necessary respect for the autonomy and responsibility of the individual. As Whitman saw it, the mission of government was to train communities through all their grades, beginning with individuals and ending there again, to rule themselves.

Democratic institutions need to evolve beyond the scope of national borders

The relationship between a butterfly and its chrysalis offers a biological analogy that could shed some light on this relationship between the ideals of democracy and the sheltering institutions of the nation state. In the closing words of hisGettysburg Address, Lincoln alluded to the broader significance of the struggle to preserve the Union for the fate of democracy across the world. In Lincolns reasoning, the function of the Union was not only to protect the rights of its citizens but also to provide a shelter for democratic movement that transcended national borders. Like a chrysalis defending the slow transformation of a caterpillar into a butterfly, the Union provided an irreplaceable shelter in which the culture and legal institutions of the United States could mature into a new kind of democracy: a new birth of freedom that would be unprecedented in size and scope. The analogy of the chrysalis and the butterfly, like so many analogies drawn from nature, entails both creation and destruction. For the butterfly to take flight, it must tear open the shelter of the chrysalis and leave it behind. What had been a shelter would become a sarcophagus if this process did not take place. The nation state, which has sheltered democracy for centuries, will become its sarcophagus if democratic institutions are not allowed to grow and evolve beyond the narrow scope of national borders.

The question that the human race faces in the twenty first century is not whether we should or should not have global governance. The global governance that we already have insures the nearly frictionless flow of goods and services around the planet by maintaining and expanding a transport and communications infrastructure that dwarfs anything seen in all of human history. The real question is whether we can make the global governance that we already have fairer, more democratic, and more effective in protecting the lives and wellbeing of the living and the yet to be born.

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Albert Einstein was right: we must democratize the UN - Democracy Without Borders